RNA nucleoprotein complexes in biological systems

RNA-nucleoprotein (RNP) complexes are pivotal to the regulation of gene expression. These multiprotein, multifunctional act as scaffolds, molecular platforms, hubs interaction between RNA and proteins. The past decade has seen an exponential increase in methodologies identify functionally characterize these complexes. In this review, we provide overview recent advances knowledge gained by characterizing important This information provided clues role sequence, structural determinants for RNA–Protein networks physiology pathophysiology. With studies implicating formation biomolecular condensates, their health disease warrants detailed structure functional investigations.